PREDICTION OF IMPAIRED LOWER-EXTREMITY FUNCTION BY GENOME AND
MICROBIOME ANALYSIS
LEGTECH
Expedient: IDI-20230068
Duration:
SABARTECH participates in a pioneering project to predict functional impairment in the elderly through genomic and microbiota analysis.
Population aging leads to an increased risk of disability, being Impaired Lower Extremity Function Impairment (ILEF) one of the main indicators of loss of autonomy in older adults. In order to develop early and personalized prediction tools, SABARTECH collaborates in an innovative project focused on the prevention of ILEF, integrating clinical, genetic and microbiome information.
This project aims to build a multivariate predictive model based on biomarkers related to muscle function, mobility and balance, allowing early identification of people at risk. In this way, it will be possible to implement tailored preventive interventions to delay or avoid the onset of disability.
SABARTECH brings its expertise in genomic and microbiota analysis, contributing to the development of advanced solutions for personalized medicine in aging. This initiative reinforces the company’s commitment to preventive health and technological innovation in the service of a better quality of life in old age.
The main objective of the LEGTECH project is to improve the early detection, diagnosis, treatment and follow-up of ILEF through the development of an omics technology for predicting the risk of developing ILEF, which will allow the identification of high-risk older adults and the development of interventions to delay or prevent ILEF.
This technology will be framed within a user-friendly Risk Prediction Calculator that will allow its use by a wide range of professionals.
The technical objectives associated with the project are as follows:
– To generate the first clinical, genomic and metagenomic curated database for functional impairment of the lower extremities.
– To build a robust database based on DNA Microarray and Exome (WESArray) and to establish a high precision genotyping system using Whole Genome DNA Microarray (WGA).
– To generate and validate an exposomic and genetic multiscale Predictive Risk algorithm for ILEF.
– Obtain CE/IVD marking for the commercialization of the final product within the EU.
The project has received funding from the European Union, through the NextGenerationEU funds, within the framework of the Recovery, Transformation and Resilience Plan, and with the support of the Ministry of Science and Innovation and the CDTI (Center for Technological Development and Innovation). This aid is part of the Recovery and Resilience Mechanism, established by Regulation (EU) 2021/241 of the European Parliament and of the Council of February 12, 2021.
The total funding amounts to 819,118.75 €, distributed between FISABIO (350,482.55 €), the Autonomous University of Madrid (242,000.00 €) and Sabartech S.L. (226,636.20 €). This investment promotes the development of innovative solutions in the field of personalized health and the prevention of functional deterioration in the elderly.
Parque Científico Universidad de Valencia, Catedrático Agustin Escardino, 9, 46980, Paterna, Valencia
info@sabartech.com
EXPEDIENT Nº: IDI-20230068
PROGRAM: ACCIÓN CONJUNTA ISCIII-CDTi 2022 del CDTi
PROJECT: PREDICTION OF IMPAIRED LOWER-EXTREMITY FUNCTION BY GENOME AND MICROBIOME ANALYSIS
OBJETIVES: Improve early detection, diagnosis, treatment and follow-up of ILEF by developing an omics technology for risk prediction.
RESULTS ACHIEVED: Omics technology for predicting the risk of developing ILEF, which makes it possible to identify high-risk older adults, and to propose interventions to delay or prevent ILEF.
THIS PROJECT HAS BEEN FINANCED WITH EUROPEAN UNION FUNDS – NextGenerationEU, UNDER THE RECOVERY AND RESILIENCE MECHANISM ESTABLISHED BY REGULATION (EU) 2021/241 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL OF 12 FEBRUARY 2021.
EXPEDIENT Nº: IMIDTA/2023/43.
PROGRAM: SME R&D PROJECTS (PIDI-CV) 2023
PROJECT: AIG-SPORT – THE NEXT GENERATION OF SPORT PERFORMANCE (AIG-SPORT)
OBJECTIVES: The generation of a new model of 5P SPORTS TECHNOLOGY to revolutionise professional and amateur sport.
RESULTS ACHIEVED: A software focused on sports performance called AIG-SPORT that aims to bring science closer to athletes through guidelines for the improvement of sports performance, athletes’ brands, the prevention of injuries related to exercise and training, the personalisation of food and supplementation plans in a much more precise way.
THIS PROJECT IS SUPPORTED BY THE EUROPEAN UNION AS IT HAS BEEN SELECTED IN THE FEDER OPERATIONAL PROGRAMME FOR THE VALENCIAN COMMUNITY 2021-2027.
Expedient Nº: INNEST/2021/292
Project: INTELLIGENT PLATFORM FOR EARLY DETECTION, DIAGNOSIS AND MONITORING OF SARCOPENIA (iSARC-GENETICS)
Supported by Agència Valenciana de la Innovació (AVI)
